Episode 3

Advancing Precision Oncology in High-Grade Serous Ovarian Cancer: Proficiency Testing for Homologous Recombination Deficiency and Evidence-Based Decision-Making

Date & Time: November 11, 2025
12-1:30 pm EST
10-11:30 am CST

Speakers:

Laura Hopkins

Laura Hopkins BSc, MSc, MD, FRCSC

Dr. Laura Hopkins is a gynecologic oncologist with the Saskatchewan Cancer Agency and a professor in the University of Saskatchewan’s College of Medicine. She is part of the Marathon of Hope Cancer Centres Network, leading a study that contributes to the network’s Gold Cohort. She completed her medical degree at the University of Toronto, followed by residency training in Obstetrics and Gynecology at McMaster University and subspecialty training in Gynecologic Oncology at the University of Toronto. Before joining the Saskatchewan Cancer Agency, she spent 18 years at The Ottawa Hospital, where she held several senior academic and leadership roles, including Vice-Chair of Obstetrics and Gynecology and Head of Gynecologic Oncology.

Since moving to Saskatoon in 2019, Dr. Hopkins has launched Saskatchewan’s first tumor bank, established its first gynecologic oncology clinical trials program, and obtained funding for a next-generation sequencer. In 2023, she initiated the province’s first investigator-led trial studying patient preferences for precision medicine in ovarian cancer — a project that has changed the standard of care for ovarian cancer treatment in Canada. Her research centers on precision oncology, pragmatic clinical trial design, informed patient decision-making, surgical safety and quality, and improving equity in cancer care access.

Tracy Stockley

Tracy Stockley PhD, FCCMG, FACMG
Scheme Director, Canadian Biomarker Quality Assurance
Professor, Department of Laboratory Medicine & Pathobiology
University Health Network, Toronto

Stockley is a molecular geneticist and Director of Hereditary Genomics in the Genome Diagnostics Division at University Health Network in Toronto. At UHN, Dr. Stockley participates in overseeing genetic testing for oncology, including hereditary cancer, companion diagnostics and the development of genomic tests for emerging biomarkers. Dr. Stockley has research and clinical interests in improving quality assurance in high-complexity laboratory testing, and engages in quality activities with multiple national and international organizations, including Health Canada, the Canadian Biomarker Quality Assurance program, the College of American Pathologists, Association for Molecular Pathology, the European Molecular Quality Network and the International Organization for Standardization (ISO). In addition, Dr. Stockley is a Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto, and is a past President of the Canadian College of Medical Geneticists (CCMG). Dr. Stockley is also a cancer survivor with a personal interest in patient support and engagement in research.

Learning Objectives:

After this episode, the participant will be able to:

  1. Outline the design and outcomes of the Saskatchewan clinical trial evaluating HRD testing and a patient decision aid to guide PARP inhibitor use in high-grade serous ovarian cancer.
  2. Describe the role of the Tumour Testing and Ovarian Cancer Drug Prediction Program in advancing precision oncology through tumor biobanking, next-generation sequencing, and evidence-based treatment selection.